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MB5-625 exam Dumps Source : C5 4.0 Project

Test Code : MB5-625
Test cognomen : C5 4.0 Project
Vendor cognomen : Microsoft
: 38 true Questions

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Microsoft Microsoft C5 4.0 Project

VNPT co-operates with overseas partners to develop ICT ambitions | killexams.com true Questions and Pass4sure dumps

VNPT is expanding co-operation with global technology agencies to understand its target to develop into a four.0 telecommunication business.   

On November 9, Vietnam Posts and Telecommunications group (VNPT) and Fujitsu from Japan signed a Memorandum of figuring out (MoU) on co-operation within the tips and verbal exchange technologies (ICT) sector.

as a consequence, the two events will travail with each different to develop initiatives regarding cloud computing, artificial intelligence, in addition to presenting functions within the IT sector.

“VNPT is making an attempt to develop into a 4.0 enterprise, specialising in supplying digital service products. alongside their present IT capabilities, the enterprise is gaining knowledge of and setting up other technologies namely AI, astronomical records, and blockchain. The industry believes that the co-operation with Fujitsu – some of the main ICT enterprises from Japan – will aid VNPT to less demanding strategy original technologies as well as curtail the time of issuing original items to the market,” pointed out Huynh Quang Liem, deputy unvarying director of VNPT.

up to now, in July 2016 VNPT and US-based Microsoft signed an MoU on strategic co-operation in cloud computing and cyber protection.

according to this MoU, Microsoft will assist VNPT strengthen and carry cloud computing-primarily based functions and execute sure cyber protection. it is going to likewise advocate in VNPT’s sage metropolis task through the Microsoft CityNext initiative to carry innovation to cities and provinces throughout Vietnam, together with sensible fitness functions, sensible transportation, sage tourism, and sage e-executive.

both corporations will boost annual plans for co-operation and establish a working community to implement the agreed plans.

VNPT’s leading enterprise sectors encompass trading in telecommunications and assistance technology products and features and multimedia, as well as consulting, designing, installing, operating, and repairing IT facilities.

in keeping with selection No.2129/2017/QD-TTg of the leading minister, approving VNPT’s restructuring draw in 2018-2020, the neighborhood will must complete equitisation in 2019.

Pham Duc long, well-known director of VNPT, pointed out that the neighborhood is trying to comprehensive the contrast of its land fund as well as different property by pass of the conclusion of the third quarter of this year and then finalise the enterprise’s valuation.

in accordance with the plan, the neighborhood will conduct the IPO through the End of subsequent 12 months with the aid of putting a 35 per cent stake on sale to buyers.

by using Ha Vy


the first evolution AI debuts at RIB's 6th iTWO World convention | killexams.com true Questions and Pass4sure dumps

No influence found, are trying original keyword!The enterprise's enterprise cloud solution MTWO, launched in collaboration with Microsoft ... iTWO four.0 is the realm's first 5D BIM industry cloud solution with AI integration for construction corporations ...

Mono 4.0.0 Will undertake Microsoft’s Open source Code | killexams.com true Questions and Pass4sure dumps

while there’s no down load hyperlink or an official announcement, the unencumber notes of the upcoming Mono 4.0.0 framework had been posted lately on the mission’s site, and they hold to admit that the changes are quite dazzling, however that Mono is not any longer a favored challenge on the open-supply group.

according to the unencumber notes, highlights of Mono 4.0.0 consist of adoption of Microsoft’s open source code, sheperd for C# 6.0, an improved IKVM.web implementation, prefatory aid for PowerPC64 Little Endian (PPC64LE), lighter debugger overhead, and floating point optimizations. The upcoming unencumber likewise gets rid of advocate for historical .web frameworks.

What the Microsoft source code adoption capability for Mono

The upcoming Mono 4.0.0 free up can exist the primary to substitute a few of its core add-ons with those launched by means of the Microsoft service provider under a free, open supply license. These comprehend Microsoft’s ReferenceSource drop, CoreFX, and CoreCLR. while Microsoft will execute a revamped version of its .net framework, Mono will nevertheless present an API (application Programming Interface) that tracks the computing device and server version of .internet.

“This capability that many of the code that we've built-in comes from the ReferenceSource drop. in the future, they are able to convey a ‘Mono Core’ alongside the same lines of .net Core to enable using the Mono runtime with the brand original library distribution gadget it truly is being developed with CoreFX. in this release, they now hold either ported components that were both incomplete or buggy in Mono and were notably convenient to port to Mono.”

if you don’t exist aware of what Mono is, they can let you know that it’s an open source implementation of the .internet framework and programming language created by pass of Microsoft. Mono lets developers create pass-platform purposes that travail on Linux, windows, and Mac OS X working methods. more details concerning the upcoming unencumber of Mono 4.0.0 will likewise exist present in the respective unlock notes.




Killexams.com MB5-625 Dumps and true Questions

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MB5-625 exam Dumps Source : C5 4.0 Project

Test Code : MB5-625
Test cognomen : C5 4.0 Project
Vendor cognomen : Microsoft
: 38 true Questions

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C5 4.0 Project

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Complement activation and effect of eculizumab in scleroderma renal exigency | killexams.com true questions and Pass4sure dumps

Devresse, Arnaud, MDa,b; Aydin, Selda, MDb,c; Le Quintrec, Moglie, MD, PhDd; Demoulin, Nathalie, MDa,b; Stordeur, Patrick, PhDe; Lambert, Catherine, MDf; Gastoldi, Sarag; Pirson, Yves, MDa,b; Jadoul, Michel, MDa,b; Morelle, Johann, MDa,b,*

Section Editor(s): Nadasdy., Tibor

1 Introduction

Systemic sclerosis (SSc) is a complex autoimmune disorder characterized by microvascular damage and progressive fibrosis of the skin and visceral organs, especially the lungs, heart, and kidneys. Scleroderma renal exigency (SRC) occurs in ∼10% of SSc patients, and is characterized by abrupt onset of hypertension, thrombotic microangiopathy (TMA), and acute kidney injury.[1] Although prognosis has improved with the consume of angiotensin-converting enzyme inhibitors, 40% of patients silent require dialysis, and 25% die within 1 year.[2] The pathogenesis of SSc remains poorly understood but a growing carcass of evidence suggests that activation of the complement system may exist involved in the disease. Here, they report the theatrical case of a juvenile patient presenting with austere SRC during pregnancy in which complement activation was comprehensively documented both in serum and in the kidney, and effectively blocked by the specific C5 complement inhibitor eculizumab.

2 Case presentation

A 28 year-old female Caucasian patient was admitted to the emergency department at 28 weeks of a 1st twin pregnancy with hypertension (220/120 mm Hg), signs of TMA, and acute kidney injury (serum creatinine 2.67 vs 0.36 mg/dL 2 months earlier).

SSc was diagnosed 3 years earlier on the basis of an acrosyndrome, sclerotic skin changes, microvascular abnormalities on nailfold capillaroscopy, and significant titers of anticentromere (197 IU/L, unvarying <7) and anti-Scl70 (>240, unvarying <7 IU/L) antibodies. She was treated with nifedipine 30 mg od for hypertension. There was no family history of autoimmune disorder, kidney disease, or TMA. The pregnancy was hitherto uncomplicated, with no proteinuria and optimal blood pressure control.

Lab tests at admission (Table 1) showed austere thrombocytopenia, microangiopathic hemolytic anemia, and ADAMTS13 activity in unvarying scope (39%), ruling out thrombotic thrombocytopenic purpura. Liver office was unaltered, C3 and C4 complement levels were decreased, and urinalysis showed a bland sediment and grievous proteinuria (4+). Cesarean delivery was performed on the day of admission because of TMA and fetal distress, and lisinopril 20 mg od and intravenous nicardipine were started. Daily plasma exchange had to exist initiated 48 hours later because biological signs of TMA persisted and AKI had progressed to anuria, requiring dialysis initiation, making the diagnosis of preeclampsia unlikely. Systematic workup likewise ruled out HIV infection, antiphospholipid syndrome, and occult infection. Ultrasound showed kidneys of unvarying size, without thrombosis of renal arteries but with global bilateral hypoperfusion. Kidney biopsy showed austere vascular changes mainly in renal arterioles and, to a lesser extent, in glomerular capillaries (Fig. 1A, B). Light microscopy showed vascular lesions of intimal thickening by myxoid tissue, onion-skinning, fibrinoid necrosis, and intraluminal thrombosis in interlobular arterioles, along with extensive ischemic damage in the glomeruli and tubules. Eleven out of the 39 glomeruli appeared necrotic while the remaining ones presented signs of glomerular ischemia, thrombosis at the vascular pole, or mesangiolysis. Approximately 25% of the cortex was necrotic. Immunofluorescence studies identified deposits of C3 (2+), C1q (2+), C4d (3+) (Fig. 1C, D), and C5-b9 deposits were observed in the endothelium of renal arterioles and in glomeruli (Fig. 1E, F).

Table 1

Table 1

Figure 1

Figure 1

Complement profile in the patient's serum sampled at admission showed, in addition to decreased levels of both C3 and C4, increased SC5b-9 levels, as well as elevated C3d/C3 and FBb/FB ratios (Table 1). Activation of the complement system was further confirmed by demonstrating the sturdy capacity of the patient's serum to induce C5b-9 deposits on cultured human microvascular endothelial cells ex vivo (Fig. 1G).[3] An extensive genetic screening found no mutation in the genes encoding the components of the alternative pathway of complement or its regulatory proteins known to exist involved in atypical hemolytic uremic syndrome (aHUS), including CFH, CFI, MCP, C3, CFB, CFH-related proteins and THBD, and anti-CFH antibodies were not detected.

Because of the theatrical clinical and histological severity of the SRC and several lines of evidence supporting complement activation, eculizumab was initiated 18 days after admission (4 weekly 900 mg infusions, followed by 1200 mg every 2 weeks) (Supplementary Fig. 1, http://links.lww.com/MD/B165). Despite prompt and optimal control of blood pressure, normalization of volume status with intermittent hemodialysis, and effectual blockade of the complement system by the C5 inhibitor (Fig. 1G), serum troponin T levels increased progressively (Supplementary Table 1, http://links.lww.com/MD/B165) and the patient developed original onset heart failure (left ventricle ejection fraction ∼22%). There was no evidence of pulmonary arterial hypertension. The patient rapidly developed acute pulmonary edema, supraventricular tachycardia followed by bradyarrhythmia and cardiac arrest. Despite early cardiopulmonary resuscitation, pacing, and an attempt of extracorporeal membrane oxygenation, the patient died from heart failure 8 weeks after the onset of the SRC. At autopsy, coronary arteries and myocardial microvasculature appeared unvarying (i.e., with no symptom of TMA or atherosclerotic disease). The pericardium was normal, but the left ventricle showed diffuse mild patchy interstitial fibrosis (Supplementary Fig. 2, http://links.lww.com/MD/B165), the typical lesion of the most austere forms of SSc-related cardiomyopathy.[4]

3 Discussion

This patient presented a austere SRC during pregnancy, with extensive lesions of TMA in the kidney. The sturdy evidence of systemic and local, intrarenal, activation of the complement system suggests it has played a role in the pathogenesis of kidney injury. Treatment with the specific C5 blocker eculizumab was associated with hematological remission of the disease and a keen diminish in C5b-9 deposits ex vivo.

The complement system is Part of innate immunity, acting as a 1st-line defense against pathogens and maintaining host homeostasis. Complement activation initiates a cascade reaction that generates bioactive components (C3b, C3a, C5a, and C5b-9) with proinflammatory, chemo-attractant, and cell-damaging functions.[5] A few observations suggested that activation of the complement system might exist involved in the pathophysiology of SSc and SRC. First, C3 and/or C4 hypocomplementemia is present in ∼15% of patients with SSc, and associated with disease severity and vascular involvement.[6,7] Second, C5b-9 deposition was detected in capillaries of skin biopsies of SSc patients but not in well subjects.[8] Third, C4d deposition was found in renal peritubular capillaries of a subset of SSc patients with a poor renal outcome.[9] In their patient, systemic complement activation during austere SRC was unequivocally demonstrated by a constellation of findings: hypocomplementemia; circulating complement profile with increased levels of SC5b-9 and increased C3d/C3 and FBb/FB ratios;[10] vascular deposition of C5b-9 in injured glomerular capillaries and renal arterioles; and the capacity of the patient's serum obtained at admission to induce SC5b-9 deposits on cultured microvascular endothelial cells.[3] These findings were reminiscent of those observed in patients with complement-mediated aHUS, the prototype of diseases resulting from ineffective protection of the endothelium from complement attack.[11] Altogether they suggested that abnormal activation of the complement system may exist involved in the pathogenesis of SRC.

Thorough assessment of complement fractions deposition in damaged vessels likewise provided clues to the mechanism underlying complement activation in this setting. Basically, 3 different pathways (classical, lectin, and alternative) can activate the complement system. They vary in their recognition target: antibodies in the classical pathway, carbohydrate residues on microorganisms in the lectin pathway, and a permanent low-level activation in the alternative pathway.[12] Activation of the classical pathway has been well documented in antibody-mediated rejection and lupus erythematosus, that is, through the C1 component and its pattern recognition molecule C1q.[5,13–15] In these situations, the deposition of C4d – a byproduct of activation of the classical and lectin pathways – in injured tissues is informative of the mechanism by which the complement system is activated and has been associated with disease severity and poor outcome.[16–19] In their patient, the coexistence of violent C4d and C1q deposits in renal arteries and glomerular capillaries demonstrated that complement activation in SRC occurred through the classical pathway. Although it is tempting to speculate that autoantibodies or immune complexes might exist liable for such activation during SRC, they cannot formally rule out the effect of hypertension-induced hemodynamic shear-stress, which has likewise been shown to activate the classical pathway of the complement system on endothelial cells.[20] The increased FBb/FB ratio found in patient's serum suggested subsequent recruitment of the alternative pathway through the C3b feedback cycle, as previously described in lupus erythematosus.[21]

Complement inhibition – on top of blockade of the renin–angiotensin system – might exist useful in austere refractory cases of SRC, when complement activation has been carefully documented.[22] The efficiency of eculizumab – a recombinant, fully humanized, monoclonal antibody directed against the human complement component C5 – was demonstrated in patients with aHUS.[23] More recent evidence likewise suggested it might exist useful in diseases driven by complement activation through the classical pathway, such as antibody-mediated rejection[24] and lupus nephritis.[25,26] In these conditions confirmatory evidence is however awaited and clinical trials are in progress. In their patient, eculizumab efficiently blocked C5b-9 deposition ex vivo, contrarily to plasma exchange, and maintained hematological remission. The requisite of recovery of renal office despite both effectual C5 blockade and prompt blood pressure control using angiotensin-converting enzyme inhibitors is likely explained by the extent of preexisting cortical necrosis. The evolution of heart failure under complement inhibition and the absence of overt myocardial vascular lesions at postmortem examination suggested an independent pathophysiological process, possibly related to abnormal vasoreactivity.[4]

In conclusion, they report a fatal case of SRC in which several lines of evidence demonstrated complement activation through the classical pathway. Further studies are needed to decipher the mechanisms of complement activation in SSc and its role in the pathogenesis of SRC, and to substantiate the potential benefit of early eculizumab administration in patients with refractory, life-threatening SRC despite the consume of angiotensin-converting enzyme inhibitors.

4 Ethics committee

The Ethics Committee of the Cliniques Universitaires Saint-Luc approved this case-report and encouraged its publication despite the absence of written informed consent from the patient – who died during the course of the disease – as the case-report ensures complete confidentiality and respect of private life, in agreement with national laws. In addition, total investigations were performed based on clinical needs.

Acknowledgements

The authors thank Fondation Saint-Luc (JM), the Fondation Horlait-Dapsens (JM), and the Fonds National pour la Recherche Scientifique (JM) and the European Union FP7 EURenOmics Project number 305608 (SG) for the support.

References 1. Mouthon L, Bussone G, Berezné A, et al Scleroderma renal crisis. J Rheumatol 2014; 41:1040–1048. 2. Denton CP, Lapadula G, Mouthon L, et al Renal complications and scleroderma renal crisis. Rheumatology (Oxford) 2009; 48 (suppl 3):iii32–iii35. 3. Noris M, Galbusera M, Gastoldi S, et al Dynamics of complement activation in aHUS and how to monitor eculizumab therapy. Blood 2014; 124:1715–1726. 4. Allanore Y, Meune C. Primary myocardial involvement in systemic sclerosis: evidence for a microvascular origin. Clin Exp Rheumatol 2010; 28:S48–S53. 5. Frémeaux-Bacchi V, Legendre CM. The emerging role of complement inhibitors in transplantation. Kidney Int 2015; 88:967–973. 6. Hudson M, Walker JG, Fritzler M, et al Hypocomplementemia in systemic sclerosis – clinical and serological correlations. J Rheumatol 2007; 34:2218–2223. 7. Cuomo G, Abignano G, Ruocco L, et al Hypocomplementemia in systemic sclerosis. Reumatismo 2008; 60:268–273. 8. Scambi C, Ugolini S, Jokiranta TS, et al The local complement activation on vascular bed of patients with systemic sclerosis: a hypothesis-generating study. PLoS One 2015; 10:e0114856. 9. Batal I, Domsic RT, Shafer A, et al Renal biopsy findings predicting outcome in scleroderma renal crisis. Hum Pathol 2009; 40:332–340. 10. Cataland SR, Holers VM, Geyer S, et al Biomarkers of terminal complement activation substantiate the diagnosis of aHUS and differentiate aHUS from TTP. Blood 2014; 123:3733–3738. 11. Noris M, Caprioli J, Bresin E, et al Relative role of genetic complement abnormalities in sporadic and familial aHUS and their repercussion on clinical phenotype. Clin J Am Soc Nephrol 2010; 5:1844–1859. 12. Noris M, Remuzzi G. Atypical hemolytic-uremic syndrome. N Engl J Med 2009; 361:1676–1687. 13. Wild G, Watkins J, Ward AM, et al Complement activation in systemic sclerosis. J Clin Lab Immunol 1990; 31:39–41. 14. Arason GJ, Geirsson AJ, Kolka R, et al Deficiency of complement-dependent prevention of immune precipitation in systemic sclerosis. Ann Rheum Dis 2002; 61:257–260. 15. Ballanti E, Perricone C, Greco E, et al Complement and autoimmunity. Immunol Res 2013; 56:477–491. 16. Feucht HE, Felber E, Gokel MJ, et al Vascular deposition of complement-split products in kidney allografts with cell-mediated rejection. Clin Exp Immunol 1991; 86:464–470. 17. Cohen D, Koopmans M, Kremer Hovinga IC, et al Potential for glomerular C4d as an indicator of thrombotic microangiopathy in lupus nephritis. Arthritis Rheum 2008; 58:2460–2469. 18. Shen Y, Chen XW, Sun CY, et al Association between anti-beta2 glycoprotein I antibodies and renal glomerular C4d deposition in lupus nephritis patients with glomerular microthrombosis: a prospective study of 155 cases. Lupus 2010; 19:1195–1203. 19. Li SJ, Liu ZH, Zen CH, et al Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection. Lupus 2007; 16:875–880. 20. Yin W, Ghebrehiwet B, Weksler B, et al Regulated complement deposition on the surface of human endothelial cells: effect of tobacco smoke and shear stress. Thromb Res 2008; 122:221–228. 21. Wilson MR, Arroyave CM, Nakamura RM, et al Activation of the alternative complement pathway in systemic lupus erythematosus. Clin Exp Immunol 1976; 26:11–20. 22. Thomas CP, Nester CM, Phan AC, et al Eculizumab for rescue of thrombotic microangiopathy in PM-Scl antibody-positive autoimmune overlap syndrome. Clin Kidney J 2015; 8:698–701. 23. Legendre CM, Licht C, Loirat C. Eculizumab in atypical hemolytic-uremic syndrome. N Engl J Med 2013; 369:1379–1380. 24. Kocak B, Arpali E, Demiralp E, et al Eculizumab for salvage treatment of refractory antibody-mediated rejection in kidney transplant patients: case reports. Transplant Proc 2013; 45:1022–1025. 25. Pickering MC, Ismajli M, Condon MB, et al Eculizumab as rescue therapy in austere resistant lupus nephritis. Rheumatology (Oxford) 2015; 54:2286–2288. 26. El-Husseini A, Hannan S, Awad A, et al Thrombotic microangiopathy in systemic lupus erythematosus: efficacy of eculizumab. Am J Kidney Dis 2015; 65:127–130. Keywords:

acute kidney injury; complement system; systemic sclerosis; thrombotic microangiopathy

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The best smart helmets | killexams.com true questions and Pass4sure dumps

It doesn’t matter if you ride a road bike, mountain bike, ebike, or motorcycle, a convincing helmet is vital to staying safe. But in this day and age, even the simple helmet is getting a high-tech makeover, with total kinds of smart elements being added. Once the stuff of science fiction, smart helmets are now a very true product, bringing built-in microphones, speakers, rear-facing cameras, and many other helpful features with them. The best smart helmets combine several of these gizmos to execute your riding suffer safer and more enjoyable.

Helmets may silent exist the bane of many a haircut but they remain a crucial Part of any rider’s wardrobe. Here, we’ve scoured the market to find the coolest helmets and accessories, total of which are available now or are currently in development. Whether you ride a bicycle or a motorcycle, read on to observe if any of them might exist a convincing proper for you.

Note: Several of these items are currently only available via crowdfunding websites such as Kickstarter and Indiegogo. Investing in these types of projects can exist a risk, and there’s no guarantee that you’ll End up receiving anything. They execute no guarantees, as they are not affiliated with any of these companies.

The Livall Bling BH60 has been a staple on the list of best smart helmets for years — and it’s for convincing reason. With its built-in LED strips on the top and rear — which can exist controlled using a remote affixed to the handlebars — riders are not only more visible, but they can witness which direction they’re turning, too. The helmet likewise works with the official Livall app (iOS/Android) to issue automatic SOS repercussion alerts should the wearer Fall or exist struck by a car. In those situations, the app automatically alerts the rider’s emergency contact to inform them of the incident.

A windbreak microphone and Bluetooth speaker even allow for hands-free calling and playback of music, as well. There’s likewise a walkie-talkie feature which allows riders to abide in contact with other Bling users in their group while on the trail or road.

If the Bling BH60 isn’t to your liking, Livall offers an array of other helmets that feature different designs, but offer the same set of features and technology. For instance, the company’s Bling MT1 was specifically made with mountain bikers in mind. There are even smart helmet options for kids, too.

Built for cycling at night, the Lumos Helmet is outfitted with revolve signals in both the front and rear, which are linked to a handlebar remote that offers several months of battery life between recharges. Automatic brake lights are likewise included, though these drain the helmet’s juice pretty quickly. To conserve battery life, Lumos does give riders the option to revolve them off.

This helmet is likewise water-resistant, allowing it to survive unexpected rain showers — or expected, if that’s how you devotion to ride. If you’re only biking to and from work, it may not exist the best selection due mainly to the fact the lights aren’t particularly visible during daytime. However, it’s silent stylish, affordable, and offers plenty of protection to poke along with its smart features.

Our complete Lumos Helmet review

Buy one now from:

Amazon Lumos

Coros Omni ($200)

View photos

Many cyclists cherish listening to music while riding, but that can exist a perilous habit, especially when traversing high-density urban areas with lots of traffic. Coros overcomes this issue by creating smart cycling helmets which allow for safe listening by using bone conduction speakers to transfer sound directly through your ear bones (weird, right?). The result is a decent listening suffer that doesn’t preclude the rider from being able to hear the environment around them.

The included smart remote and mount snaps easily onto your handlebars and can control volume, playback, and phone calls, while the inclusion of a wind-resistant precision microphone means you can hold conversations on-the-go. devotion the Livall Bling, there’s likewise an onboard repercussion sensor that automatically notifies emergency contacts in the event of a collision. The Omni is a nice upgrade over the brand’s previous release, the Linx, adding LED lights for better visibility and compatibility with the more robust Coros app (iOS/Android).

Buy one now from:

Amazon Coros

Sena Momentum ($200) and X1 ($200)

sena momentum and x1

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Whether you pedal your bike or fire up its engine, Sena has a smart helmet for you. The company makes noggin protection for both cyclists and bikers, both of which Come packed with some seriously innovative technology. The Momentum is Sena’s flagship motorcycle helmet, while the X1 is its top cycling option, with both sporting Bluetooth connectivity via a smartphone to offer the faculty to listen to music, hold phone calls, receive GPS navigation instructions, and more. Both helmets are likewise equipped with onboard video cameras, FM radios, and an intercom system that allows hands-free communication with other riders.

Buy one now from:

Amazon Sena

Airwheel C5 ($200)

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Built for cycling, skateboarding, climbing, or just about any other outdoor activity where a helmet may exist required, the Airwheel C5 packs a lot of features into a relatively lightweight and good-looking design. Not only does this helmet allow the wearer to hold phone calls completely handsfree, its onboard Bluetooth speaker can facilitate music and podcast playback, as well.

Best of all, the C5 features an onboard 2K high-def camera for recording video and taking photos and comes with 128 GB of built-in storage. Its rechargeable battery provides up to three hours of recording time, while integrated WiFi connectivity makes it a pushover to upload any video or images to another device for editing. Airwheel even save thought into the helmet’s ventilation system, making it restful to wear for extended periods of time.

Buy one now from:

Amazon

Helmets that could exist coming soon Livemap ($2,000)

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Helmet-mounted displays will eventually exist devotion flat screens — once cutting edge tech that has now become commonplace. Once projection and smart technologies become easier to manage, head-up displays are likely to exist everywhere. Livemap is a prototype motorcycle helmet that uses augmented reality for navigation; street names, speed, and turn-by-turn directions are displayed directly over the world around you, negating the requisite to shift focus from the road. tedious to a desist and you can pop up a map to give it a more thorough examination. The helmet likewise includes a microphone and speakers for voice control, phone calls, and listening to music.

The catch? It’s not available yet and it costs a fortune. You can reserve one now for a $500 deposit, though we’re not sure when it’ll actually launch. The company says that it is coming in 2018, but the device has already been delayed. For now, check out the Livemap website (you can silent contribute to the project) to abide up to date on developments. The helmet’s software is based on the Android platform, so perhaps developers will eventually exist able to build apps specifically for Livemap.

Pre-order it now from:

LiveMap

Cross Helmet X1 ($1,599)

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The Cross Helmet X1 is easily the coolest (and most futuristic) looking helmet on their list, allowing riders to explore devotion an action hero and, potentially ride devotion one too. Advertised as a “next-generation helmet,” the X1 will feature sound control, Bluetooth connectivity, a dedicated smartphone app, and — wait for it — a 360-degree scope of vision, which is achieved via a rear camera displayed at the top of the visor, complete with a digital clock and navigational data.

In combination with the wide-view visor, riders will exist able to observe the entire road, making the X1 one of the safest helmets ever built – assuming it works as intended of course. The app controls uproar isolation, too, making it possible to screen out the sound of traffic or open your ears when cruising through more serene environments. Additional features devotion group talk functionality and safety lighting will only execute the X1 more attractive when it starts shipping in 2019.

Check it out via:

Cross Helmet

Skully Fenix AR ($1,899)

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Another high-tech motorcycle helmet scheduled for release in 2018 is the Skully Fenix AR. This device features a head-up parade in the contour of a small, integrated screen that not only offers turn-by-turn navigational cues but provides 360-degree awareness thanks to a rear-facing camera built-into the back of the helmet. Music streaming and handsfree phone calls are likewise Part of the package, as well.

Made from a carbon fiber shell, the Fenix AR promises to exist lightweight and restful to wear. It includes a visor that resists fogging, emergency quick-release straps, a chin skirt, and is available in six sixes. Preorders are being taken now, with a promised delivery date of summer in the United States and Canada, with European models coming later.

Check it out via:

Skully Technologies

Accessories to smarten your helmet Ahead ($159)

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By now, they can probably total agree: Smart helmets are awesome. What’s not awesome is spending tons of money to supplant your favorite domepiece with a high-tech head-cage that may or may not proper comfortably. Ahead, a Samsung-funded Kickstarter project led by a group called Analogue Plus, looks to remedy that problem. It’s a Little device that affixes to an existing helmet — a variety of different mounts are included, so most any helmet is compatible — and utilizes an oscillator to conduct sound through the helmet and into your ears.

Connecting Ahead to your smartphone via the dedicated app allows users to listen to music, execute phone calls, activate your digital assistant, and track various fitness metrics, among other things. Dual narrow-angle microphones on either side of the device likewise ensure that ambient uproar is eliminated, even at speeds up to 40 miles per hour. Plus, it’s durable and IP45 rated for water and dust, so it should survive most rides, even in inclement conditions.

Buy it now from:

Amazon

Lightmode Proton Kit ($129)

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Lightmode is an attachment designed to travail with any motorcycle helmet. This is more decorative than “smart” technology. impeccable for Tron cosplay, you merely hold to glue these lights on with the provided two-part adhesive to ensure they hold at elevated speeds. A supple sticky mount holds a tiny controller for the lights, the latter of which last up to 13 hours on two AA batteries and features three modes (constant, tedious blink, and speedy blink).

Lightmode likewise comes in three kit sizes, with the larger Proton kit affording you about 15 feet of piping in one of seven colors. The company crushed its initial Kickstarter crusade in 2014 and has since upgraded total of its options with a new, more efficient, controller. The kits are available in an array of different colors and options for variety of helmet types, with prices starting at $129.

Buy it now from:

LightMode

BE-Link ($50)

View photos

The BE-Link is another Kickstarter project and though it isn’t a smart helmet per se, it is a convenient add-on that delivers some smart features. The BE-Link is essentially a pair of wired headphones that can exist installed in any helmet with a die-cut Velcro cradle or the dedicated BE-Link Cradle mount ($15). One of those two options works with pretty much every helmet on the market, which means you can add Bluetooth to your rig, or quickly transfer it between different helmets as needed. And, since you’re putative to supplant your bike helmet every three years, this could save you a few bucks in the long run.

An updated 4.0 version of the BE-Link is likewise available, offering improved sound, more control, and extra features, for $149.

Buy it now from:

Amazon exist Headwear

Helmet ideas that didn’t travail out Skully AR-1

View photos

Prior to closing its doors in April of 2017, the San Francisco-based startup Skully was in the process of developing the AR-1, a crazy smart motorcycle helmet that looked every bit of a game changer. The helmet, which raised more than $2 million in funding via Indiegogo, featured an integrated heads-up parade which projected a live feed from the helmet’s rearview camera onto the inside of an electrochromic visor.

The helmet likewise supported Bluetooth, allowing you to hold phone calls and listen to music sans cables. Skully did actually ship some units to a few fortunate riders but after funding grew thin and founder Marcus Weller was unable to nigh a deal with Chinese company LeSports, the venture (unfortunately) collapsed.

Forcite Alpine

Do they hold snowy mountains in Australia? Turns out, the confess is yes. So, Sydney-based startup Forcite created a smart snow helmet dubbed the Alpine, tricked it out with tons of chilly features, then took it to Kickstarter. The Alpine is outfitted with a 4K action cam (with image stabilization and slow-mo capabilities), a helmet-to-helmet walkie-talkie, fog lights, and a smattering of useful sensors, including an altimeter and an repercussion sensor.

The Forcite team was seeking $200,000 and ended up roughly 75 percent of the pass to its funding goal. Often, companies modify their product (and their goal) and start another round of funding. This doesn’t appear to exist the case with the Alpine, however, which sort of fell off the kisser of the Earth after it canceled funding in October of 2015. At $800, the Alpine wasn’t going to exist cheap but it’s silent disappointing to observe it Fall by the wayside.


Program test analysis and technical counsel on EOSIO | killexams.com true questions and Pass4sure dumps

Abstract

Huobi Research conducted a research and analysis of the Dawn 3.0 version of EOSIO through evaluating its platform performance in multiple scenarios.

Based on their test conditions (AWS servers in LAN environment), EOSIO can gain 1900 TPS at its best performance. There is a discrepancy between their result and the dispassionate TPS (3000), optimal TPS (6000), and theoretically optimal TPS (8000) result in the Dawn 3.0 documentation, but the worst performance of 1000 TPS described in the document can exist stably reached.

Along with increasing server configuration, the maximum TPS of the system will likewise increase. At the same time, if the conditions allow, augment server resources of the super node (Block Producer) obtains better overall performance. Therefore, in the main network environment, they recommend using servers with the highest possible configuration.

Decentralized deployment can result in an adverse effect on performance. Since the current EOSIO program code does not advocate multi-threading, only a separate -core of CPUs can exist utilized, so parallel computing cannot exist used to help efficiency. In this situation, decentralized deployments, especially adding super-nodes, carry out not enhance performance for alleviating separate server pressure . Instead, they augment CPU overhead and may hold a negative repercussion on TPS.

Reasonable consume of JIT will enhance performance. This routine can reduce the CPU usage and augment TPS to a inescapable extent, but its repercussion on stability is likewise noticeable.

1. Foreword

Currently EOS super-node crusade is rolling complete stream. According to statistics, as of May 2, there are 102 active bidding organizations . At the same time, block.one released EOSIO’s Dawn 3.0 version in April and plans to poke live on main network in June.

Earlier, numbers of communities hold set up test networks and tested EOSIO performances, especially on number of transactions per second (TPS). However, TPS performance is topic to many conditions such as compiler parameters, server hardware, operating systems, and networks. The test results revealed more of the “theoretical fuel consumption” under laboratory conditions (reference: https://steemit.com/cn/@eoseoul/bmt-eosio-tps-by-eoseoul-block-one-jit).

Unlike many of the previous tests, the research and analysis conducted by us Huobi Research does not focus on whether EOSIO can achieve the 1M TPS declared by Dan Larimer’s team. Instead, they anatomize their observations of the performance indicators of Dawn 3.0 under different conditions to propose ideas and suggestions for future main network architecture and server configuration. Huobi Research will publish result up study if original versions such as Dawn 4.0 is released.

It should likewise exist famous that the indicator data obtained from this particular test is not and should not exist regarded as proof or confirmation of the final performance result of the EOSIO platform or project. Hereby declare.

2. Main Conclusions

After analyzing their test results, they obtained and proposed the following main conclusions and technical advices:

l Based on their test conditions (AWS servers in LAN environment), EOSIO can gain 1900 TPS at its best performance. There is a discrepancy between their result and the dispassionate TPS (3000), optimal TPS (6000), and theoretically optimal TPS (8000) result in the Dawn 3.0 documentation (Reference: https://medium.com/eosio/eosio-dawn-3-0-now-available-49a3b99242d7), but worst scenario 1000 TPS described in the document can exist stably reached.

Along with increasing server configuration, the maximum TPS of the system will likewise increase. At the same time, if the conditions allow, augment server resources of the super-node (Block Producer) obtains better overall performance. Therefore, in the main network environment, they recommend using servers with the highest possible configuration.

Decentralized deployment can result in an adverse effect on performance. Since the current EOSIO program code does not advocate multi-threading, only a single-core of CPUs can exist utilized, so parallel computing cannot exist used to help efficiency. In this situation, decentralized deployments, especially adding super-nodes, carry out not enhance performance for alleviating separate server pressure . Instead, they augment CPU overhead and may hold a negative repercussion on TPS.

Reasonable consume of JIT will enhance performance. This routine can reduce the CPU usage and augment TPS to a inescapable extent, but its repercussion on stability is likewise noticeable.

3. Descriptions on test conditions

3.1 Testing Program Version

The testing program is version dawn-v3.0.0 of EOSIO

3.2 Hardware Environment

Amazon AWS. Listed below according to the flat of configuration:

AWS EC2 t2.large (hereinafter referred to as the low-profile server): 2-core 2.3 GHz, Intel Broadwell E5–2686v4 CPU, 8GB RAM

AWS EC2 C5.4xlarge (hereinafter referred to as high-profile server): 16-core 3GHz, Intel Xeon Platinum 8124M CPU, 32GB RAM

We used 10Gbps LAN between servers, communication retard (ping) is less than 1ms.

The operating system is Ubuntu 16.04.

3.3 Testing Methods and Tools

We used the txn_test_gen test plug-in appliance provided by block.one to forward test transaction data and celebrate performance indicators such as actual TPS and system CPU usage (Reference: https://github.com/EOSIO/eos/wiki/Testnet-Single-Host-Multinode; https://gist.github.com/spoonincode/fca5658326837b76fd744d39b2a25b4e).

4. Test Scenarios and Results Analysis

4.1 Scenario 1

Deploy a "super node" (Block Producer, hereinafter referred to as BP) and a unvarying node (Full Node, hereinafter referred to FN) on the same low-profile server.

The results achieved by sending test data through FN are as follows:

4.1a

The results achieved by sending test data through BP are as follows:

4.1b

It is worth noting that when the transmission rate is 1700, BP’s CPU has been used 100%, but BP silent shows stable processing capacity. At the same time, the usage rate of the CPU where the FN’s processing is located fluctuates greatly and cannot exist synchronized from BP to screen in time. With the system running, the screen height incompatibility between BP and FN will increase.

Through the results of this scenario, they Come to the following conclusion:

Because the current EOSIO program does not advocate multi-threading, it is not possible to consume the parallel computing of multi-core CPUs to help efficiency.

BP's CPU usage is lower than FN's CPU usage. This finding seems to exist the balky of the usual understanding of "super nodes." They believe that the reason lies in two nodes undertaking different works: BP's design philosophy is to ensure transaction security and integrity (not losing blocks), and FN is designed to provide services externally, requiring transaction signatures, serialization , verification, etc.;

When the deals are transmitted through BP and FN respectively, there are significant differences in the platform TPS, which is likewise related to the above-mentioned tasks such as the signature and serialization of transactions.

4.2 Scenario 2

Improve server configuration and continue to celebrate system performance. Deploy a screen Producer (hereinafter referred to as BP) and a complete Node (hereinafter referred to as FN) on the same high-profile server.

The results achieved by sending test data through FN are as follows:

4.2a

The results achieved by sending test data through BP are as follows:

4.2b

Comparing with Scenario 1, they observed that the maximum TPS of the system increases when the server configuration increases.

4.3 Scenario 3

4.3a

The results achieved by sending test data through BP are as follows:

4.3b

Comparing with Scenario 2, they observed that the CPU usage in this scenario is slightly higher than that of the same condition, and this is believed to exist caused by the cost of processing network traffic. separate deployment in this scenario does not affect TPS significantly. This likewise relates to the current single-threaded approach: when BP and FN are deployed on the same server , they carry out not compete for CPU resources. Therefore, if the current code does not advocate multi-threading, it is possible that separate deployment will not enhance performance, but instead augment the CPU overhead.

4.4 Scenario 4

In Scenario 3, BP and FN are deployed on the same configuration server. Scenarios 4 and 5 deploy BP and FN on different servers with different configurations. In this scenario, BP is deployed on a low-profile server and FN is deployed on a high-profile server.

The results achieved by sending test data through FN are as follows:

4.4a

The results achieved by sending test data through BP are as follows:

4.4b

4.5 Scenario 5

In this scenario, FN is deployed on a low-profile server and BP is deployed on a high-profile server.

The results achieved by sending test data through FN are as follows:

4.5a

The results achieved by sending test data through BP are as follows:

4.5b

Comparing Scenario 4 and Scenario 5, they believe that allocating more resources for BP creates better overall performance.

4.6 Scenario 6

The above scenarios utilized two servers (1 BP, 1 FN). In this scenario they add in one FN to deploy one BP and two FNs on three high-profile servers.

The results achieved by sending test data through FN are as follows:

4.6a

The results achieved by sending test data through BP are as follows:

Comparing the results with that of Scenario 2, they conclude that adding a server in a single-threaded scenario increases CPU overhead and may negatively affect TPS.

4.7 Scenario 7

The above scenarios are separate BP cases. They augment the nodes to 2 BPs and 2 FNs in this scenario

The results achieved by sending test data through FN are as follows:

4.7a

The results achieved by sending test data through BP are as follows:

4.7b

Comparing with the results in Scenario 6, it can exist seen that the CPU usage after adding one more BP will increase, and the maximum TPS achieved will likewise exist significantly reduced, indicating that increasing BP has a greater repercussion on performance. If multiple nodes are distributed in off-site main network environments, complex environmental factors such as network delays will intensify the impact. Thus, higher requirements on node server resources is imposed.

4.8 Scenario 8

Dawn 3.0 description file mentioned that the default interpreter of this version was changed from JIT to Binaryen WebAssembly, which will weaken performance but augment stability and reduce the retard when compiling smart contracts. In Scenario 8, they change the operating parameters of scenario 2 to JIT and execute observation.

The results achieved by sending test data through FN are as follows:

4.8a

The results achieved by sending test data through BP are as follows:

4.8b

Comparing to Scenario 2, they observe that CPU usage is significantly reduced. However, test interruption occurs when the CPU is not fully used, which proves that JIT does affect system stability.



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