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clinical nurse specialists and nurse practitioners are both advanced celebrate nurses who every so often toil in lots of of the identical forms of fitness custody amenities. both require an MSN, or master of science in nursing, diploma and each can moreover contain direct affected person care. despite the fact, there are a few huge changes between both professions.
COLUMBIA, S.C. — South Carolina is proposing legalizing clinical marijuana to aid people who undergo from separate perpetual illnesses and ache.
So, what would the bill basically do? And who would improvement from it?
Let's win a deeper parade on the SC Compassionate custody Act, invoice S.366 within the SC Senate, added by using Senators Tom Davis (R-forty six), Brad Hutto (D-40), Paul Campbell (R-44), Marlon Kimpson (D-forty two), Darrell Jackson (D-21), Mia McLeod (D-22), and M.B. Matthews (D-forty five).
Davis says the bill is the most strictly regulated and socially conservative clinical marijuana bill within the nation and reflects the subculture of South Carolinians. The invoice has gone through four years of subcommittee processes with a all lot of hours of testimony and legislative opinions included into the latest edition.
The senators hope that Gov. Henry McMaster will signal the invoice into legislation in 2019.
What the bill would permit
up to 2 oz. of scientific hashish within the styles of vaporized flower or oil, gel caps, suppositories, patches, edibles or topical lotions.
Smoking cannabis would no longer subsist allowed. it would subsist illegal for a cardholder to smoke hashish or exhaust a device to facilitate the smoking of hashish. A violation of this subsection is punishable by way of a civil first-class of up to $a hundred and fifty.
Distribution of medical marijuana to someone for leisure exhaust could subsist unlawful, with fines as much as $5,000 and/or up to 5 years in reformatory.
Who it will cover
There should subsist a strict latitude of situations for the approval of exhaust of clinical marijuana, and no need might subsist allowed without healthcare professional supervision and authorization.
in keeping with the invoice: stories posted due to the fact that the 1999 Institute of drugs document proceed to demonstrate the therapeutic cost of hashish in treating a wide selection of debilitating clinical circumstances. These comprise aid of the neuropathic ache that frequently fails to respond to typical remedies; a discount in patients' reliance on opiate-based painkillers; decreased signs and even complete remission from Crohn's disease; and reduction of ascetic nausea, thereby expanding the probabilities of patients carrying on with existence-saving medicine regimens.
'Debilitating scientific situation' capacity one or more of the following:
melanoma currently requiring remedy
a neurological ailment or sickness
post-anxious stress disorder (PTSD)
cachexia or wasting syndrome
sickle mobile anemia
severe or persistent nausea in someone who isn't pregnant and that's regarding quit of life or hospice care, or the particular person is bedridden or domestic positive as a result of the condition
a perpetual scientific circumstance causing extreme and confirmed muscle spasms
or any persistent or debilitating ailment or medical condition for which an opioid is presently or may well subsist prescribed via a physician in accordance with often permitted specifications of care.
sufferers in quest of scientific marijuana fill to fill written certification.
within the invoice, 'written certification' skill a document signed by a physician, stating that the affected person has been diagnosed with a debilitating medical situation and will improvement from the exhaust of clinical cannabis. The certification may subsist made most efficient throughout a bona fide physician-affected person relationship, must specify the qualifying affected person's debilitating clinical condition, and fill to subsist up to date yearly for each qualifying patient by means of the certifying doctor. If the qualifying patient is expected to recuperate from the debilitating scientific situation within a 12 months of the written certification, no longer together with if the patient may additionally fade into remission due to clinical hashish medicine, or the qualifying affected person is not anticipated to advantage from clinical hashish for a complete year, the written certification shall specify that fact.
sufferers may subsist issued an identification card with the prescription for medical marijuana.
becoming scientific marijuana
The invoice states "all cultivation, harvesting, processing, and packaging of hashish must win zone in a relaxed facility at a actual address supplied to the branch and SLED each and every over the processing facility or cultivation core's registration process. The snug facility may subsist accessed only by way of agents of the scientific cannabis establishment, legislation enforcement, emergency personnel, and adults who are twenty-one years of age and older who are accompanied with the aid of clinical cannabis institution agents. enterprises are province to random inspections by way of SLED.
"To evade diversion and present protection to public safety, the DHEC shall require the exhaust of a separate true-time, seed-to-sale monitoring system used by using each and every scientific cannabis companies and the branch that complies with medical health insurance Portability and Accountability Act (HIPAA) instructions, is hosted on a platform that enables for dynamic allocation of materials, offers facts redundancy, and is in a position to recovering from natural disasters inside hours."
give chain auditing techniques dote this are a edition of Blockchain expertise that permits the monitoring of items via each and every phases of creation from increase to distribution, together with earnings, recalls and theft.
under the bill, DHEC shall require that the gadget subsist able to:
tracking each and every plants, products, applications, sufferers, waste, transfers, conversions, applications, sales, and returns, and each and every with provocative identification numbers;
tracking lot and batch assistance throughout the total chain of custody except the point of sale to a cardholder;
tracking each and every product, conversions, and derivatives during the complete seed-to-sale chain of custody;
tracking plant, batch, and product destruction;
monitoring transportation of product;
performing complete batch recollect tracking capabilities that need to subsist capable of naturally determine the entire following details relating to the particular batch theme to the finish not forget: each and every bought product; product attainable for sale (product that is in entire inventory, but now not offered); product that's in the transfer method; toil in development (product it's being transformed); and raw material (product that is within the submit-harvest process, reminiscent of drying, trimming, and curing);
reporting and tracking loss, theft, or diversion of product containing hashish;
reporting and monitoring each and every inventory discrepancies to the branch;
reporting and tracking each and every revenue and refunds to the department;
receiving trying out results electronically from independent testing laboratories by way of a secure utility program interface (API) into the seed-to-sale monitoring device, and directly attaching the testing consequences to the supply batch and/or sample;
restricting the altering of watch at various results with the aid of the operator;
offering the department with precise-time access to the database;
proposing actual-time analytics to the branch concerning key efficiency warning signs including, however not restricted to: complete each day earnings; total plants in creation; total plants destroyed; and complete stock changes
presenting different assistance precise by the department.
doling out scientific marijuana
each dispensary should condense with or employ as a minimum one pharmacist, healthcare professional assistant, nurse practitioner, or medical nurse specialist, who has accomplished a branch-authorised medical cannabis carrying on with education route. The pharmacist, surgeon assistant, nurse practitioner, or medical nurse specialist need to subsist moderately accessible to counsel and educate patients, in adult or by means of telemedicine. A pharmacist, surgeon assistant, nurse practitioner, or medical nurse specialist may condense with dissimilar dispensaries.
Funding the scientific marijuana software
A South Carolina clinical hashish software Fund might subsist established to compose inevitable the provision of cash necessary to fulfill the DHEC's responsibilities beneath this text. each and every monies collected pursuant to this article must subsist deposited into the fund. The cash ought to subsist used completely for the direct and roundabout charges linked to the implementation, administration, and enforcement of this text.
Revenues generated in extra of the amount essential to implement and implement this act can subsist distributed every three months as follows: (a) fifty % to the South Carolina law Enforcement Division; (b) twenty-5 p.c to the South Carolina branch of training; and (c) twenty-five % to the situation time-honored Fund.
All revenue of medical hashish are province to a six percent excise tax at the point of sale.
A 9-member clinical hashish Advisory Board may subsist created that can subsist required to meet at the least twice a yr to subsist able to evaluate petitions to add qualifying conditions, consult with consultants in South Carolina and different states with medical hashish classes about ongoing analysis within the container, and, if fundamental, hang public hearings earlier than vote casting on whether so as to add current qualifying circumstances.
The board contributors would serve four 12 months phrases and the board need to subsist constituted of one appointment from each and every of the following:
the executive of situation law Enforcement Division or his designee;
The director of the branch or his designee;
Two licensed clinical doctors approved to drill in this State, appointed by means of the Governor and tested by means of the Senate;
One licensed medical professional of osteopathic medicine approved to celebrate in this State, appointment through the Governor and established by means of the Senate;
One licensed pharmacist approved to celebrate during this State, appointed by way of the Governor and demonstrated by using the Senate;
One cardholder, appointed by way of the Governor and tested by way of the Senate;
One representative of a registered clinical hashish institution, appointed with the aid of the Governor and validated with the aid of the Senate;
One consultant from a municipality of this State; appointed via the Governor and verified by way of the Senate
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MOLINE — Her job lets her finish what many of her colleagues wish they had time to do.
Cassie Burns, 33, of Milan, works as a clinical nurse specialist at UnityPoint Health-Trinity Moline.
"I'm a nurse navigator who works with breast-cancer patients and with people having high risks for cancer," she said.
Beginning with a patient's first day of treatment, Burns goes with the patient to each and every appointments, even if they are with people who aren't affiliated with Trinity, she said.
It gives Burns the haphazard to compose much more of a personal connection, which is something most nurses wish they had time for, she said.
She gives patients each and every the information she can give them about what threatens their health.
Previously, Burns had been an oncology nurse for 11 years, starting prerogative after graduating from Black Hawk College. She accepted her navigator position five years ago.
Navigators are a relatively current position that was created within the past 10 years or so, she said.
"Most hospitals find that it improves quality," Burns said. "It's an outside-of-the-box nurse. It's what you compose of it. It's making positive people fill what they need and that each and every the physicians are on the same page."
Burns said she had thought about becoming a pediatric nurse, but she switched to health-care nursing after learning more about it.
"It's different to custody for these patients," Burns said. "They fill different attitudes toward the process, and lots of needs that I entangle to help."
"I dote this job," she said. "I really dote to arrive to work. I bask in it, and don't dread it all. I really don't know what I would finish without it."
Her toil schedule allows her to finish a lot of community outreach, too.
"I will finish a lot of education about breast-cancer screening," she said.
She has spoken at programs sponsored by churches and at other events with attendance ranging from five to 20 people. She's available to converse to any size group; muster her at 309-779-5080 to set something up.
Burns moreover serves as an education ambassador for a national nonprofit organization named quick-witted Pink, joining it about four years ago.
“We should study that!”: How a nurse-scientist found her passion
Nurse-scientist Kimberly Pyke-Grimm draws on her clinical suffer when studying how teens, immature adults and families compose decisions about cancer care.
Author Erin DigitalePublished on February 20, 2019February 20, 2019
My favorite flash in the Harry Potter sequence is the sorting hat scene from Harry Potter and the Sorcerer's Stone, when each and every the current Hogwarts students are magically sorted into their houses. After a few moments of sitting in suspense with the chatty sorting hat on his head, Harry ends up in Gryffindor with his friends Ron and Hermione. Phew!
Because I entangle to interview people who dote their jobs, I dote to quiz how they "got sorted" into the toil they do. I received an especially provocative retort during a recent conversation with Kimberly Pyke-Grimm, PhD, a nurse-scientist at Lucile Packard Children's Hospital Stanford.
My tale explains:
When Pyke-Grimm began working in pediatric oncology, she was struck by the painful uncertainties families faced as they made treatment choices for their children. Parents might agonize over whether to enroll a immature child in a clinical trial, grapple with the selection between different cancer treatments or battle complicated feelings while deciding on end-of-life care.
'As a bedside nurse, I really bore witness to them struggling to compose some of those decisions,' Pyke-Grimm said.
...Pyke-Grimm... earned a master’s degree in nursing, an suffer that hooked her on nursing research. When [she and her husband] moved to Winnipeg, Canada, in 1991, Pyke-Grimm collaborated with Lesley Degner, PhD, a professor of nursing at the University of Manitoba. Degner studied decision-making in adults with cancer. Together, she and Pyke-Grimm extended these investigations to parents of immature kids with cancer.
'I was so very fortunate, working with Lesley,' Pyke-Grimm said. “I felt like, ‘This is my home: decision-making research.'
Today, Pyke-Grimm has extended her research to quiz how teenagers and immature adults with cancer compose decisions about their care. She spends 40 percent of her time on research and 60 percent on clinical care, and continues to bring a nurse's perspective to her research:
Almost every day that I toil as a clinical nurse specialist, I esteem ‘We should study that!’ or ‘Why is it we’re doing it this way?’
Photo by Steve Fisch
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Ipsen (Euronext: IPN; ADR: IPSEY) today announced that they are looking forward to revealing 17 presentations that detail their research into neuroendocrine tumors (NETs) at the 16th European Neuroendocrine Tumor Society (ENETS) Annual Conference, which is taking space in Barcelona, Spain between 6th-8th March 2019.
One of the key presentations, titled (Abstract #H14) ‘Development of a current and improved delivery system for lanreotide autogel/depot to further enhance custody for patients with NETs and acromegaly’, reports results from five separate, but complementary studies designed to inform and test enhancements to the existing Somatuline® Autogel® (lanreotide) pre-filled syringe.1
Input from patients and their caregivers, as well as nurses and other healthcare professionals, was used to design a current pre-filled syringe1 that was submitted to the European Union as a sort II variation via a work-sharing procedure with HPRA (Ireland) as the reference country. Following a positive outcome of the work-sharing procedure, each member situation would esteem a national approval. Notable current features are modified ergonomics and handling, a needle shield removal system, an injection process with plunger back and heightened ease of use.1
"It is their mission to ensure patients continue to receive optimized custody as they navigate the challenges of vital with NETs and acromegaly,” said Sotirios Stergiopoulos, Chief Medical Officer at Ipsen. "The data they are sharing at this year’s ENETS conference underscores their commitment to understanding the patient suffer and to supporting a multidisciplinary treatment approach to compose treatment administration as simple as viable whether in hospital or at home.”
"For nurses and other healthcare practitioners treating patients with NETs or acromegaly, the value of innovation across the entire treatment landscape supports their faculty to provide the best custody for their patients,” said Daphne T Adelman, Clinical Nurse Specialist from Northwestern University in Chicago, U.S. and one of the authors of the study. "As a nurse who administers treatments to patients often, efficient pre-filled syringes allow me to redeem time and focus on patients and their needs.”
Also, being highlighted are results from:
(Abstract #H18) Tumour growth rate (TGR) to monitor growth/predict response to lanreotide autogel (LAN) exhaust before, during and after peptide receptor radionuclide therapy (PRRT) in advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs): data from PRELUDE
This abstract has been selected for a poster walk during ENETS’ scientific program and will report effectiveness data and post-hoc analyses of tumor growth rate (TGR) as a measure of response to LAN–PRRT (lanreotide autogel – peptide receptor radionuclide therapy).
(Abstract #M03) ATLANT, facet 2 study combination ordeal between long acting somatostatin analogue (SSA) lanreotide (LAN) and temozolomide (TMZ) in progressive thoracic (lung / thymus) well differentiated NET (carcinoid) (TNETS).
(Abstract #F22) Exploratory assessment of the clinical value of baseline (BL) circulating tumour cells (CTC) to call symptomatic response in pts with functioning midgut neuroendocrine tumours (NETs) receiving lanreotide autogel (LAN): CALM-NET study results
In addition to these posters, Ipsen will participate data from the following 13 company sponsored or supported studies and literature reviews:
(Abstract #H17) Safety and Efficacy of 14-Day Dosing Interval of Lanreotide Autogel/Depot (LAN) For Patients With Pancreatic or Midgut Neuroendocrine Tumours (NETs) Progressing on LAN Every 28 Days: The Prospective, Open-label, International, facet 2 CLARINET metier Study
(Abstract #P04) Lanreotide autogel 120mg (LAN) in patients (pts) with locally advanced or metastatic gastroenteropancreatic neuroendocrine tumours (GEP-NETs): prospective observational NETways study
(Abstract #D13) Satisfaction Survey of Administration Modes for Long-Acting (LA) Somatostatin Analog (SSA) Therapy in Patients (pts) with Neuroendocrine Tumuors (NETs): Results of Cognitive Interviews With Patients and Nurses
(Abstract #J15) The sequel of Carcinoid Syndrome Diarrhea (CSD) Interventions on Patient suffer Outcomes: a Systematic Literature Review (SLR)
(Abstract #J08) Differential Diagnosis (DDx) of Carcinoid Syndrome Diarrhea (CSD): a Systematic Literature Review (SLR)
(Abstract #H25) Evaluation of the exhaust of resources and costs associated with Uncontrolled or Controlled Carcinoid Syndrome (CS) in patients (pts) with Neuroendocrine Tumours (NETs) in Spain: RECOSY study
(Abstract #F10) Relationship between biomarkers and number of liver metastases at the time of diagnosis of small intestinal neuroendocrine tumors
(Abstract #A11) Evaluation of gene expression changes associated with response to somatostatin analogues (SSAs) in gastrointestinal (GI) neuroendocrine tumors (NETs)
(Abstract #J07) Long-term Treatment with Telotristat Ethyl (TE) in Patients with Carcinoid Syndrome (CS) Symptoms: Results from TELEPATH Study
(Abstract #P05) TELEFIRST: A randomized facet III clinical ordeal of Lanreotide (LAN) combined with Telotristat ethyl (TE) or placebo (PBO) for the First-line treatment in patients (pts) with advanced well-differentiated (wd) small intestinal neuroendocrine tumours (siNET) with highly-functioning carcinoid syndrome (CS)
(Abstract #K30) OPS-C-001: A facet I/II Study To Investigate Safety, Tolerability, Biodistribution, Dosimetry and prefatory Efficacy of 177Lu-OPS201 for the Therapy of Somatostatin Receptor (SSTR)-Positive Neuroendocrine Tumours (NETs)
(Abstract #P08) Study to evaluate the optimal dose of 68Ga-OPS202 as a PET imaging agent in patients with GEP-NETs
(Abstract #D33) Establishment of a NET data foundation in a German tertiary referral center; prefatory results
Somatuline® Autogel® is made of the energetic gist lanreotide, which is a long-acting somatostatin analogue that inhibits the secretion of growth hormone and inevitable hormones secreted by the digestive system. The main indications of Somatuline® and Somatuline® Autogel® are:2
The treatment of individuals with acromegaly when the circulating levels of Growth Hormone (GH) and/or Insulin-like Growth Factor-1 (IGF-1) remain abnormal after surgery and/or radiotherapy, or in patients who otherwise require medical treatment.
The treatment of grade 1 and a subset of grade 2 (Ki-67 index up to 10%) gastroenteropancreatic neuroendocrine tumors (GEP-NETs) of midgut, pancreatic or unknown inception where hindgut sites of inception fill been excluded, in adult patients with unresectable locally advanced or metastatic disease.
The treatment of symptoms associated with neuroendocrine (particularly carcinoid) tumors.
Important Safety Information
The minute recommendations for the exhaust of Somatuline Autogel are described in the Summary of Product Characteristics (SmPC), available here.
Xermelo® is a novel, orally administered, inhibitor of the enzyme tryptophan hydroxylase (TPH). Through inhibition of TPH, the rate-limiting step in the synthesis of serotonin, Xermelo® was designed to reduce the production of serotonin within neuroendocrine tumors.
Xermelo® (telotristat ethyl) is commercialized by Ipsen in each and every territories excluding the United States and Japan, where Lexicon retains the rights. Lexicon has approval for Xermelo® in the U.S. as a first and only orally administered therapy for the treatment of carcinoid syndrome diarrhea in combination with somatostatin analog (SSA) therapy in adults inadequately controlled by SSA therapy.
Xermelo® is approved in Europe for the treatment of carcinoid syndrome diarrhea in patients inadequately controlled by somatostatin analogue therapy.
Important Safety Information
The minute recommendations for the exhaust of Xermelo are described in the Summary of Product Characteristics (SmPC), available here.
References1 Data on File. ENETS ‘192 Somatuline Autogel SmPC. November 20183 Xermelo SmPC. January 2019
Ipsen is a global specialty-driven biopharmaceutical group focused on innovation and Specialty Care. The group develops and commercializes innovative medicines in three key therapeutic areas - Oncology, Neuroscience and Rare Diseases. Its commitment to Oncology is exemplified through its growing portfolio of key therapies for prostate cancer, neuroendocrine tumors, renal cell carcinoma and pancreatic cancer. Ipsen moreover has a well-established Consumer Healthcare business. With total sales over €2.2billion in 2018, Ipsen sells more than 20 drugs in over 115 countries, with a direct commercial presence in more than 30 countries. Ipsen's R&D is focused on its innovative and differentiated technological platforms located in the heart of the leading biotechnological and life sciences hubs (Paris-Saclay, France; Oxford, UK; Cambridge, US). The Group has about 5,700 employees worldwide. Ipsen is listed in Paris (Euronext: IPN) and in the United States through a Sponsored level I American Depositary Receipt program (ADR: IPSEY). For more information on Ipsen, visit www.ipsen.com.
Forward Looking Statement
The forward-looking statements, objectives and targets contained herein are based on the Group’s management strategy, current views and assumptions. Such statements involve known and unknown risks and uncertainties that may occasions actual results, performance or events to differ materially from those anticipated herein. each and every of the above risks could affect the Group’s future faculty to achieve its pecuniary targets, which were set assuming reasonable macroeconomic conditions based on the information available today. exhaust of the words "believes", "anticipates" and "expects" and similar expressions are intended to identify forward-looking statements, including the Group’s expectations regarding future events, including regulatory filings and determinations. Moreover, the targets described in this document were prepared without taking into account external growth assumptions and potential future acquisitions, which may alter these parameters. These objectives are based on data and assumptions regarded as reasonable by the Group. These targets depend on conditions or facts likely to happen in the future, and not exclusively on historical data. Actual results may depart significantly from these targets given the episode of inevitable risks and uncertainties, notably the fact that a promising product in early development facet or clinical ordeal may quit up never being launched on the market or reaching its commercial targets, notably for regulatory or competition reasons. The Group must countenance or might countenance competition from generic products that might translate into a loss of market share. Furthermore, the Research and development process involves several stages each of which involves the substantial risk that the Group may fail to achieve its objectives and subsist forced to abandon its efforts with regards to a product in which it has invested significant sums. Therefore, the Group cannot subsist inevitable that favourable results obtained during pre-clinical trials will subsist confirmed subsequently during clinical trials, or that the results of clinical trials will subsist adequate to demonstrate the safe and efficient nature of the product concerned. There can subsist no guarantees a product will receive the necessary regulatory approvals or that the product will prove to subsist commercially successful. If underlying assumptions prove inaccurate or risks or uncertainties materialize, actual results may differ materially from those set forth in the forward-looking statements. Other risks and uncertainties comprise but are not limited to, general industry conditions and competition; general economic factors, including interest rate and currency exchange rate fluctuations; the impact of pharmaceutical industry regulation and health custody legislation; global trends toward health custody cost containment; technological advances, current products and patents attained by competitors; challenges inherent in current product development, including obtaining regulatory approval; the Group's faculty to accurately call future market conditions; manufacturing difficulties or delays; pecuniary instability of international economies and sovereign risk; dependence on the effectiveness of the Group’s patents and other protections for innovative products; and the exposure to litigation, including patent litigation, and/or regulatory actions. The Group moreover depends on third parties to develop and market some of its products which could potentially generate substantial royalties; these partners could behave in such ways which could occasions damage to the Group’s activities and pecuniary results. The Group cannot subsist inevitable that its partners will fulfil their obligations. It might subsist unable to obtain any capitalize from those agreements. A default by any of the Group’s partners could generate lower revenues than expected. Such situations could fill a negative impact on the Group’s business, pecuniary position or performance. The Group expressly disclaims any obligation or undertaking to update or revise any forward-looking statements, targets or estimates contained in this press release to reflect any change in events, conditions, assumptions or circumstances on which any such statements are based, unless so required by applicable law. The Group’s traffic is theme to the risk factors outlined in its registration documents filed with the French Autorité des Marchés Financiers. The risks and uncertainties set out are not exhaustive and the reader is advised to advert to the Group’s 2017 Registration Document available on its website (www.ipsen.com).
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